Immunopathogenesis of Eosinophilic Esophagitis

Lymphocytic esophagitis mimicking eosinophilic esophagitis

A 74-year-old male with a history of dysphagia for 3 years presented with acute food impaction. Endoscopy showed a tight distal stricture with course rings at the middle third of the esophagus. Biopsies taken from the middle third of the esophagus showed marked infiltration of the intraepithelial lymphocytes mainly in a peripapillary distribution. The immunostains showed presence of CD3 and CD5...

Eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last decade. Diagnosis of the disorder is dependent on the patient's clinical manifestations and histologic findings on esophageal mucosal biopsies. Patients with eosinophilic esophagitis should be referred to both an allergist and gastroenterologist for optimal management, wh...

Eosinophilic esophagitis.

Eosinophilic esophagitis: A subset of eosinophilic gastroenteritis.

Eosinophilic gastroenteritis (EG) was first described over 50 years ago. Despite its long history, it remains an ill-defined and poorly understood entity. EG can present in a number of ways, none of which are exclusive to the disorder. EG has features of allergy and immune dysregulation but does not clearly fit into the category of allergic or immune disorder. While EG has been reported to affe...

Barrett's esophagus, reflux esophagitis, and eosinophilic esophagitis.

o r t R s h m f 3 o b Many new and exciting endoscopy-related studies on Barrett’s esophagus, reflux esophagitis, and eosinophilic esophagitis were presented during the 2012 Digestive Disease Week (DDW; 19-22 May, San Diego, California, USA). Endoscopic research in Barrett’s esophagus mainly focused on surveillance, detection, and ablation therapy, while clinical studies in eosinophilic esophag...